RAB8A Break Apart FISH Probe
Empire Genomics’ RAB8A Break Apart FISH Probe is designed to flank the RAB8A gene and is typically used for detecting RAB8A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAB8ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RAB8ABA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RAB8A
Gene Name: RAB8A, Member RAS Oncogene Family
Chromosome: CHR19: 16222489-16244445
Locus: 19p13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: RAB8A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAB8A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping