R2 FISH Probe
The R2 FISH probe is designed to hybridize to the R2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CD1E-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CD1E-20-RE | 20 (40 μL) | 200 μL | ||
CD1E-20-GO | 20 (40 μL) | 200 μL | ||
CD1E-20-GR | 20 (40 μL) | 200 μL | ||
CD1E-20-AQ | 20 (40 μL) | 200 μL | ||
CD1E-20-DIG | 20 (40 μL) | 200 μL | ||
CD1E-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: CD1E
Gene Name: CD1e Molecule
Chromosome: CHR1: 158323485-158327343
Locus: 1q23.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: R2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD1E-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping