PYHIN1 Break Apart FISH Probe
Empire Genomics’ PYHIN1 Break Apart FISH Probe is designed to flank the PYHIN1 gene and is typically used for detecting PYHIN1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PYHIN1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-GORE | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-GROR | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-REGO | 20 (40 μL) | 200 μL |
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| PYHIN1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PYHIN1
Gene Name: Pyrin And HIN Domain Family Member 1
Chromosome: CHR1: 158901336-158946849
Locus: 1q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PYHIN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PYHIN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping