PYHIN1 FISH Probe
The PYHIN1 FISH probe is designed to hybridize to the PYHIN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PYHIN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-RE | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-GO | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-GR | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PYHIN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PYHIN1
Gene Name: Pyrin And HIN Domain Family Member 1
Chromosome: CHR1: 158901336-158946849
Locus: 1q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PYHIN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PYHIN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping