PYCARD Break Apart FISH Probe
Empire Genomics’ PYCARD Break Apart FISH Probe is designed to flank the PYCARD gene and is typically used for detecting PYCARD rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PYCARDBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-GORE | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-ORGR | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-REGO | 20 (40 μL) | 200 μL |
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| PYCARDBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PYCARD
Gene Name: PYD And CARD Domain Containing
Chromosome: CHR16: 31212806-31214097
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PYCARD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PYCARD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping