PWRN1 FISH Probe
The PWRN1 FISH probe is designed to hybridize to the PWRN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PWRN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-RE | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-GO | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-GR | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PWRN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is located in the Prader-Willi syndrome (PWS) region of chromosome 15, which is known to undergo imprinting. The transcript is believed to be non-coding. It is bi-allelically expressed in testis and kidney, but mono-allelically expressed from the paternal allele in brain. This gene is poly-adenylated and is known to undergo alternative splicing. Transcript variants may represent part of a complex imprinting center-SNURF-SNRPN transcription unit. The contribution of this gene to the PWS phenotype is unknown, but it has been suggested that it may play a role in establishing paternal imprinting in the PWS region, perhaps by maintaining the paternal allele in an open chromatin configuration. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: PWRN1
Gene Name: Prader-Willi Region Non-protein Coding RNA 1
Chromosome: CHR15: 24803303-24832926
Locus: 15q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PWRN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PWRN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping