PVT1 FISH Probe
The PVT1 FISH probe is designed to hybridize to the PVT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PVT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PVT1-20-RE | 20 (40 μL) | 200 μL |  |
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| PVT1-20-GO | 20 (40 μL) | 200 μL |  |
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| PVT1-20-GR | 20 (40 μL) | 200 μL |  |
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| PVT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PVT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PVT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: PVT1
Gene Name: Pvt1 Oncogene (non-protein Coding)
Chromosome: CHR8: 128806778-129113499
Locus: 8q24.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PVT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PVT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping