PUS10 Break Apart FISH Probe
Empire Genomics’ PUS10 Break Apart FISH Probe is designed to flank the PUS10 gene and is typically used for detecting PUS10 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PUS10BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PUS10BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PUS10BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PUS10BA-20-GORE | 20 (40 μL) | 200 μL |
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| PUS10BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PUS10BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PUS10BA-20-ORGR | 20 (40 μL) | 200 μL |
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| PUS10BA-20-REGO | 20 (40 μL) | 200 μL |
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| PUS10BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
Gene Details
Gene Symbol: PUS10
Gene Name: Pseudouridylate Synthase 10
Chromosome: CHR2: 61167547-61245365
Locus: 2p16.1-p15
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PUS10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PUS10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping