PTPRK FISH Probe
The PTPRK FISH probe is designed to hybridize to the PTPRK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPRK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPRK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPRK
Gene Name: Protein Tyrosine Phosphatase, Receptor Type K
Chromosome: CHR6: 128289923-128841870
Locus: 6q22.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPRK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPRK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping