PTPRF FISH Probe
The PTPRF FISH probe is designed to hybridize to the PTPRF gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPRF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPRF-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPRF
Gene Name: Protein Tyrosine Phosphatase, Receptor Type F
Chromosome: CHR1: 43996546-44089343
Locus: 1p34.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPRF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPRF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping