PTPRB FISH Probe
The PTPRB FISH probe is designed to hybridize to the PTPRB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPRB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPRB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: PTPRB
Gene Name: Protein Tyrosine Phosphatase, Receptor Type B
Chromosome: CHR12: 70910631-71031220
Locus: 12q15
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPRB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPRB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping