PTPN6 Break Apart FISH Probe
Empire Genomics’ PTPN6 Break Apart FISH Probe is designed to flank the PTPN6 gene and is typically used for detecting PTPN6 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN6BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PTPN6BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPN6
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 6
Chromosome: CHR12: 7055739-7070479
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PTPN6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping