PTPN6 FISH Probe
The PTPN6 FISH probe is designed to hybridize to the PTPN6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPN6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPN6
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 6
Chromosome: CHR12: 7055739-7070479
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping