PTPN21 Break Apart FISH Probe
Empire Genomics’ PTPN21 Break Apart FISH Probe is designed to flank the PTPN21 gene and is typically used for detecting PTPN21 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPN21BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-GORE | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-ORGR | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-REGO | 20 (40 μL) | 200 μL |
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| PTPN21BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPN21
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 21
Chromosome: CHR14: 88932121-89021123
Locus: 14q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN21 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN21-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping