PTPN21 FISH Probe
The PTPN21 FISH probe is designed to hybridize to the PTPN21 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN21-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPN21-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPN21
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 21
Chromosome: CHR14: 88932121-89021123
Locus: 14q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN21 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN21-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping