PTPN18 Break Apart FISH Probe
Empire Genomics’ PTPN18 Break Apart FISH Probe is designed to flank the PTPN18 gene and is typically used for detecting PTPN18 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPN18BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-GORE | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-GROR | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-REGO | 20 (40 μL) | 200 μL |
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| PTPN18BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: PTPN18
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 18
Chromosome: CHR2: 131113579-131132982
Locus: 2q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping