PTPN11 Break Apart FISH Probe
Empire Genomics’ PTPN11 Break Apart FISH Probe is designed to flank the PTPN11 gene and is typically used for detecting PTPN11 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPN11BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-GORE | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-GROR | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-REGO | 20 (40 μL) | 200 μL |
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| PTPN11BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: PTPN11
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 11
Chromosome: CHR12: 112856535-112947717
Locus: 12q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping