PTK2B FISH Probe
The PTK2B FISH probe is designed to hybridize to the PTK2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTK2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-RE | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-GO | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-GR | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTK2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTK2B
Gene Name: Protein Tyrosine Kinase 2 Beta
Chromosome: CHR8: 27168998-27316908
Locus: 8p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTK2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTK2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping