PSPC1 FISH Probe
The PSPC1 FISH probe is designed to hybridize to the PSPC1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PSPC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-RE | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-GO | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-GR | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PSPC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PSPC1
Gene Name: Paraspeckle Component 1
Chromosome: CHR13: 20248891-20357159
Locus: 13q12.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PSPC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSPC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping