PSENEN Break Apart FISH Probe
Empire Genomics’ PSENEN Break Apart FISH Probe is designed to flank the PSENEN gene and is typically used for detecting PSENEN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSENENBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSENENBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PSENENBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PSENENBA-20-GORE | 20 (40 μL) | 200 μL |
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| PSENENBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PSENENBA-20-GROR | 20 (40 μL) | 200 μL |
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| PSENENBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PSENENBA-20-REGO | 20 (40 μL) | 200 μL |
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| PSENENBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: PSENEN
Gene Name: Presenilin Enhancer Gamma-secretase Subunit
Chromosome: CHR19: 36236493-36237903
Locus: 19q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PSENEN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSENEN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping