PSAP FISH Probe
The PSAP FISH probe is designed to hybridize to the PSAP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PSAP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PSAP-20-RE | 20 (40 μL) | 200 μL |  |
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| PSAP-20-GO | 20 (40 μL) | 200 μL |  |
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| PSAP-20-GR | 20 (40 μL) | 200 μL |  |
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| PSAP-20-AQ | 20 (40 μL) | 200 μL |  |
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| PSAP-20-DIG | 20 (40 μL) | 200 μL |  |
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| PSAP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: PSAP
Gene Name: Prosaposin
Chromosome: CHR10: 73576054-73611082
Locus: 10q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PSAP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping