PRSS2 Break Apart FISH Probe
Empire Genomics’ PRSS2 Break Apart FISH Probe is designed to flank the PRSS2 gene and is typically used for detecting PRSS2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRSS2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-GORE | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-GROR | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-REGO | 20 (40 μL) | 200 μL |
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| PRSS2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: PRSS2
Gene Name: Protease, Serine 2
Chromosome: CHR7: 142479907-142481378
Locus: 7q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRSS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRSS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping