PRMT6 Break Apart FISH Probe
Empire Genomics’ PRMT6 Break Apart FISH Probe is designed to flank the PRMT6 gene and is typically used for detecting PRMT6 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRMT6BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-GORE | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-GROR | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-REGO | 20 (40 μL) | 200 μL |
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| PRMT6BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: PRMT6
Gene Name: Protein Arginine Methyltransferase 6
Chromosome: CHR1: 107599266-107601916
Locus: 1p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRMT6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRMT6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping