PRMT6 FISH Probe
The PRMT6 FISH probe is designed to hybridize to the PRMT6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRMT6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-RE | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-GO | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-GR | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRMT6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: PRMT6
Gene Name: Protein Arginine Methyltransferase 6
Chromosome: CHR1: 107599266-107601916
Locus: 1p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRMT6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRMT6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping