PRKN FISH Probe
The PRKN FISH probe is designed to hybridize to the PRKN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKN-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKN-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKN-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKN-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKN-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRKN
Gene Name: Parkin RBR E3 Ubiquitin Protein Ligase
Chromosome: CHR6: 162727801-161347416
Locus: 6q26
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping