PRKCZ FISH Probe
The PRKCZ FISH probe is designed to hybridize to the PRKCZ gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCZ-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKCZ-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRKCZ
Gene Name: Protein Kinase C Zeta
Chromosome: CHR1: 1981908-2116834
Locus: 1p36.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKCZ FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKCZ-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping