PRKCI FISH Probe
The PRKCI FISH probe is designed to hybridize to the PRKCI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCI-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKCI-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRKCI
Gene Name: Protein Kinase C Iota
Chromosome: CHR3: 169940219-170023770
Locus: 3q26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKCI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKCI-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping