PRKAB2 Break Apart FISH Probe
Empire Genomics’ PRKAB2 Break Apart FISH Probe is designed to flank the PRKAB2 gene and is typically used for detecting PRKAB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKAB2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-GORE | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-REGO | 20 (40 μL) | 200 μL |
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| PRKAB2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: PRKAB2
Gene Name: Protein Kinase AMP-activated Non-catalytic Subunit Beta 2
Chromosome: CHR1: 146626684-146644129
Locus: 1q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKAB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKAB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping