PPM1L Break Apart FISH Probe
Empire Genomics’ PPM1L Break Apart FISH Probe is designed to flank the PPM1L gene and is typically used for detecting PPM1L rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPM1LBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-GORE | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-GROR | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-REGO | 20 (40 μL) | 200 μL |
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| PPM1LBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: PPM1L
Gene Name: Protein Phosphatase, Mg2+/Mn2+ Dependent 1L
Chromosome: CHR3: 160473995-160788817
Locus: 3q25.33-q26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PPM1L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PPM1L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping