PPM1B FISH Probe
The PPM1B FISH probe is designed to hybridize to the PPM1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPM1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-RE | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-GO | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-GR | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| PPM1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PPM1B
Gene Name: Protein Phosphatase, Mg2+/Mn2+ Dependent 1B
Chromosome: CHR2: 44395999-44461742
Locus: 2p21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PPM1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PPM1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping