PPARA FISH Probe
The PPARA FISH probe is designed to hybridize to the PPARA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPARA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PPARA-20-RE | 20 (40 μL) | 200 μL |  |
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| PPARA-20-GO | 20 (40 μL) | 200 μL |  |
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| PPARA-20-GR | 20 (40 μL) | 200 μL |  |
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| PPARA-20-AQ | 20 (40 μL) | 200 μL |  |
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| PPARA-20-DIG | 20 (40 μL) | 200 μL |  |
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| PPARA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PPARA
Gene Name: Peroxisome Proliferator Activated Receptor Alpha
Chromosome: CHR22: 46546498-46639653
Locus: 22q13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PPARA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PPARA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping