POU5F1 FISH Probe
The POU5F1 FISH probe is designed to hybridize to the POU5F1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POU5F1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-RE | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-GO | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-GR | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-AQ | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-DIG | 20 (40 μL) | 200 μL |  |
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| POU5F1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
Gene Details
Gene Symbol: POU5F1
Gene Name: POU Class 5 Homeobox 1
Chromosome: CHR6_mcf_hap5: 2514036-2520393
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: POU5F1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: POU5F1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping