PON1 FISH Probe
The PON1 FISH probe is designed to hybridize to the PON1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PON1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PON1-20-RE | 20 (40 μL) | 200 μL |  |
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| PON1-20-GO | 20 (40 μL) | 200 μL |  |
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| PON1-20-GR | 20 (40 μL) | 200 μL |  |
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| PON1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PON1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PON1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: PON1
Gene Name: Paraoxonase 1
Chromosome: CHR7: 94927668-94953884
Locus: 7q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PON1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PON1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping