POLH Break Apart FISH Probe
Empire Genomics’ POLH Break Apart FISH Probe is designed to flank the POLH gene and is typically used for detecting POLH rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLHBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLHBA-20-AQOR | 20 (40 μL) | 200 μL |
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| POLHBA-20-GOGR | 20 (40 μL) | 200 μL |
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| POLHBA-20-GORE | 20 (40 μL) | 200 μL |
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| POLHBA-20-GRGO | 20 (40 μL) | 200 μL |
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| POLHBA-20-GROR | 20 (40 μL) | 200 μL |
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| POLHBA-20-GRRE | 20 (40 μL) | 200 μL |
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| POLHBA-20-REGO | 20 (40 μL) | 200 μL |
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| POLHBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: POLH
Gene Name: DNA Polymerase Eta
Chromosome: CHR6: 43543877-43588260
Locus: 6p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: POLH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: POLH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping