POLG Break Apart FISH Probe
Empire Genomics’ POLG Break Apart FISH Probe is designed to flank the POLG gene and is typically used for detecting POLG rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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POLGBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
POLGBA-20-AQOR | 20 (40 μL) | 200 μL | ||
POLGBA-20-GOGR | 20 (40 μL) | 200 μL | ||
POLGBA-20-GORE | 20 (40 μL) | 200 μL | ||
POLGBA-20-GRGO | 20 (40 μL) | 200 μL | ||
POLGBA-20-GRRE | 20 (40 μL) | 200 μL | ||
POLGBA-20-ORGR | 20 (40 μL) | 200 μL | ||
POLGBA-20-REGO | 20 (40 μL) | 200 μL | ||
POLGBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: POLG
Gene Name: DNA Polymerase Gamma, Catalytic Subunit
Chromosome: CHR15: 89859535-89878026
Locus: 15q26.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: POLG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: POLG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping