POLG FISH Probe
The POLG FISH probe is designed to hybridize to the POLG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POLG-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| POLG-20-RE | 20 (40 μL) | 200 μL |  |
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| POLG-20-GO | 20 (40 μL) | 200 μL |  |
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| POLG-20-GR | 20 (40 μL) | 200 μL |  |
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| POLG-20-AQ | 20 (40 μL) | 200 μL |  |
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| POLG-20-DIG | 20 (40 μL) | 200 μL |  |
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| POLG-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: POLG
Gene Name: DNA Polymerase Gamma, Catalytic Subunit
Chromosome: CHR15: 89859535-89878026
Locus: 15q26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: POLG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: POLG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping