POF1B Break Apart FISH Probe
Empire Genomics’ POF1B Break Apart FISH Probe is designed to flank the POF1B gene and is typically used for detecting POF1B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POF1BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| POF1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| POF1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| POF1BBA-20-GORE | 20 (40 μL) | 200 μL |
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| POF1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| POF1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| POF1BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| POF1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| POF1BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: POF1B
Gene Name: POF1B, Actin Binding Protein
Chromosome: CHRX: 84532394-84634748
Locus: Xq21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: POF1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: POF1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping