PNPO Break Apart FISH Probe
Empire Genomics’ PNPO Break Apart FISH Probe is designed to flank the PNPO gene and is typically used for detecting PNPO rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PNPOBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PNPOBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PNPOBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PNPOBA-20-GORE | 20 (40 μL) | 200 μL |
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| PNPOBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PNPOBA-20-GROR | 20 (40 μL) | 200 μL |
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| PNPOBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PNPOBA-20-REGO | 20 (40 μL) | 200 μL |
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| PNPOBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: PNPO
Gene Name: Pyridoxamine 5'-phosphate Oxidase
Chromosome: CHR17: 46018888-46026674
Locus: 17q21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PNPO FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PNPO-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping