PNPLA1 Break Apart FISH Probe
Empire Genomics’ PNPLA1 Break Apart FISH Probe is designed to flank the PNPLA1 gene and is typically used for detecting PNPLA1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PNPLA1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-GORE | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-GROR | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-REGO | 20 (40 μL) | 200 μL |
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| PNPLA1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Details
Gene Symbol: PNPLA1
Gene Name: Patatin Like Phospholipase Domain Containing 1
Chromosome: CHR6: 36210944-36276372
Locus: 6p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PNPLA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PNPLA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping