PNP FISH Probe
The PNP FISH probe is designed to hybridize to the PNP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PNP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PNP-20-RE | 20 (40 μL) | 200 μL |  |
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| PNP-20-GO | 20 (40 μL) | 200 μL |  |
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| PNP-20-GR | 20 (40 μL) | 200 μL |  |
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| PNP-20-AQ | 20 (40 μL) | 200 μL |  |
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| PNP-20-DIG | 20 (40 μL) | 200 μL |  |
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| PNP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PNP
Gene Name: Purine Nucleoside Phosphorylase
Chromosome: CHR14: 20937537-20946165
Locus: 14q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PNP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PNP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping