PMKA FISH Probe
The PMKA FISH probe is designed to hybridize to the PMKA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PMVK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PMVK-20-RE | 20 (40 μL) | 200 μL |  |
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| PMVK-20-GO | 20 (40 μL) | 200 μL |  |
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| PMVK-20-GR | 20 (40 μL) | 200 μL |  |
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| PMVK-20-AQ | 20 (40 μL) | 200 μL |  |
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| PMVK-20-DIG | 20 (40 μL) | 200 μL |  |
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| PMVK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Details
Gene Symbol: PMVK
Gene Name: Phosphomevalonate Kinase
Chromosome: CHR1: 154897207-154909484
Locus: 1q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PMKA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PMVK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping