PLOD2 Break Apart FISH Probe
Empire Genomics’ PLOD2 Break Apart FISH Probe is designed to flank the PLOD2 gene and is typically used for detecting PLOD2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLOD2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-GORE | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-REGO | 20 (40 μL) | 200 μL |
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| PLOD2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PLOD2
Gene Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Chromosome: CHR3: 145787227-145879282
Locus: 3q24
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLOD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLOD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping