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PLOD2 FISH Probe

The PLOD2 FISH probe is designed to hybridize to the PLOD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
PLOD2-20-OR  (Standard Design) 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL
PLOD2-20-OR 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PLOD2

Gene Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

Chromosome: CHR3: 145787227-145879282

Locus: 3q24

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PLOD2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PLOD2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping