PLK3 Break Apart FISH Probe
Empire Genomics’ PLK3 Break Apart FISH Probe is designed to flank the PLK3 gene and is typically used for detecting PLK3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLK3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLK3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PLK3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PLK3BA-20-GORE | 20 (40 μL) | 200 μL |
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| PLK3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PLK3BA-20-GROR | 20 (40 μL) | 200 μL |
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| PLK3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PLK3BA-20-REGO | 20 (40 μL) | 200 μL |
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| PLK3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: PLK3
Gene Name: Polo Like Kinase 3
Chromosome: CHR1: 45266035-45271667
Locus: 1p34.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLK3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLK3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping