PLCG2 FISH Probe
The PLCG2 FISH probe is designed to hybridize to the PLCG2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLCG2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-RE | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-GO | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-GR | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLCG2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
Gene Details
Gene Symbol: PLCG2
Gene Name: Phospholipase C Gamma 2
Chromosome: CHR16: 81812898-81991899
Locus: 16q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PLCG2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLCG2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping