PLCG1 Break Apart FISH Probe
Empire Genomics’ PLCG1 Break Apart FISH Probe is designed to flank the PLCG1 gene and is typically used for detecting PLCG1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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PLCG1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-GORE | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-GROR | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-REGO | 20 (40 μL) | 200 μL | ||
PLCG1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PLCG1
Gene Name: Phospholipase C Gamma 1
Chromosome: CHR20: 39766160-39804357
Locus: 20q12
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLCG1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLCG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping