PLCG1 FISH Probe
The PLCG1 FISH probe is designed to hybridize to the PLCG1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLCG1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLCG1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PLCG1
Gene Name: Phospholipase C Gamma 1
Chromosome: CHR20: 39766160-39804357
Locus: 20q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLCG1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLCG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping