PLAUR FISH Probe
The PLAUR FISH probe is designed to hybridize to the PLAUR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLAUR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-RE | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-GO | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-GR | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLAUR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PLAUR
Gene Name: Plasminogen Activator, Urokinase Receptor
Chromosome: CHR19: 44150246-44174498
Locus: 19q13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLAUR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLAUR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping