PLAU FISH Probe
The PLAU FISH probe is designed to hybridize to the PLAU gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLAU-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLAU-20-RE | 20 (40 μL) | 200 μL |  |
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| PLAU-20-GO | 20 (40 μL) | 200 μL |  |
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| PLAU-20-GR | 20 (40 μL) | 200 μL |  |
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| PLAU-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLAU-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLAU-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: PLAU
Gene Name: Plasminogen Activator, Urokinase
Chromosome: CHR10: 75670861-75677258
Locus: 10q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLAU FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLAU-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping