PLA2G4A Break Apart FISH Probe
Empire Genomics’ PLA2G4A Break Apart FISH Probe is designed to flank the PLA2G4A gene and is typically used for detecting PLA2G4A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLA2G4ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-GORE | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-GROR | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-REGO | 20 (40 μL) | 200 μL |
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| PLA2G4ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Details
Gene Symbol: PLA2G4A
Gene Name: Phospholipase A2 Group IVA
Chromosome: CHR1: 186798031-186958113
Locus: 1q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLA2G4A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLA2G4A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping